Aicar (also known as AICAR or Acadesine) is a compound that activates AMP-activated protein kinase (AMPK), an enzyme involved in cellular energy homeostasis. It has been studied for potential benefits in metabolic regulation, endurance enhancement, and muscle performance.

AICAR Nasal Spray – Potential Uses & Considerations

• Possible Applications:
  • Cognitive Enhancement: Some research suggests AMPK activation may support brain health and neuroprotection.
  • Metabolic Benefits: May aid in fat metabolism and insulin sensitivity.
  • Anti-Aging & Longevity: AMPK activation is linked to autophagy and cellular repair.
• Nasal Spray Advantages:
  • Faster Absorption: Bypasses the digestive system, potentially increasing bioavailability.
  • Brain Targeting: Intranasal delivery may enhance direct effects on the central nervous system (CNS).
• Current Status:
  • Not FDA-approved for any medical use.
  • Primarily used in research settings (e.g., metabolic studies, sports science).
  • Gray Market Availability: Some nootropic/supplement vendors sell it, but quality and safety are unverified.
• Risks & Side Effects:
  • Lack of Human Safety Data: Long-term effects are unknown.
  • Possible Hypoglycemia: Since AICAR affects metabolism, it could lower blood sugar.
  • Muscle Fatigue: Some users report excessive tiredness after use.