Description

Pinealon Nasal Spray Delivery

Pinealon (also spelled Pinealone) is a synthetic tripeptide (Lys-Glu-Asp) with neuroprotective, anti-aging, and cognitive-enhancing effects. Originally developed in Russia, it is used to slow brain aging, improve memory, and support neuronal repair.

Nasal spray delivery is gaining interest because of its direct pathway to the brain (via the blood-brain barrier and olfactory nerves), potentially enhancing bioavailability compared to oral or injectable routes.

1. How Pinealon Nasal Spray Works

  • Mechanism:
    • Reduces oxidative stress in neurons
    • Enhances neuroplasticity (learning & memory)
    • May stimulate telomerase activity (anti-aging effect)
    • Modulates glutamate receptors (neuroprotection)
  • Nasal Absorption Benefits:
    • Bypasses the digestive system
    • May reach the brain faster than injections (intranasal peptides can enter via the olfactory or trigeminal nerve pathways)

2. Pinealon Nasal Spray Dosage & Protocol

Since Pinealon is not FDA-approved, dosing is based on Russian clinical studies, biohacker reports, and peptide clinic protocols.

Common Dosage Ranges:

Form Dosage Frequency Cycle Length
Nasal Spray 100–300 mcg (0.1–0.3 mg) 1–2x daily 10–30 days
Subcutaneous Injection 2–5 mg/day 1x daily 10–20 days
Oral (Less Effective) 5–10 mg/day 1–2x daily Low absorption

Typical Nasal Spray Protocol:

  • 100–200 mcg per spray (1 spray per nostril, 1–2x daily)
  • Used for 10–30 days, followed by a break (to prevent receptor desensitization)
  • Best taken in the morning or before cognitive work

3. Effectiveness: Nasal vs. Injection

Factor Nasal Spray Injection
Bioavailability ~30–50% (estimated) ~80–100%
Brain Uptake Speed Faster (direct pathway) Slower (systemic)
Convenience No needles Requires injections
Reported Effects Subtle but noticeable Stronger (studies)
  • Nasal spray is more convenient for daily cognitive support.
  • Injection may be better for stronger neuroprotective effects (e.g., post-stroke recovery).

4. Benefits of Pinealon

  • Anti-brain aging (may slow cognitive decline)
  • Memory & focus improvement (anecdotal reports)
  • Neuroprotection after injury/stroke (Russian studies)
  • Mild anti-anxiety & mood stabilization
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