Pinealon–  (also spelled Pinealone)

Synthetic tripeptide (Lys-Glu-Asp) with neuroprotective, anti-aging, and cognitive-enhancing effects.

Originally developed in Russia, it is researched for the following effects

• Slow brain aging
• Improve memory, and
• Support neuronal repair

Nasal spray delivery is gaining interest because of its direct pathway to the brain (via the blood-brain barrier and olfactory nerves), potentially enhancing bioavailability compared to oral or injectable routes.

1. How Pinealon Works

• Mechanism:
  • Reduces oxidative stress in neurons
  • Enhances neuroplasticity (learning & memory)
  • May stimulate telomerase activity (anti-aging effect)
  • Modulates glutamate receptors (neuroprotection.

Since Pinealon is not FDA-approved, dosing is based on Russian clinical studies, and peptide clinic protocols.

 Studied Effectiveness: Nasal vs. Injection

• Injection may be better for stronger neuroprotective effects (e.g., post-stroke recovery).